Bayesian Shrinkage Estimation of the Relative Abundance of mRNA Transcripts Using SAGE
نویسندگان
چکیده
منابع مشابه
Bayesian shrinkage estimation of the relative abundance of mRNA transcripts using SAGE.
Serial analysis of gene expression (SAGE) is a technology for quantifying gene expression in biological tissue that yields count data that can be modeled by a multinomial distribution with two characteristics: skewness in the relative frequencies and small sample size relative to the dimension. As a result of these characteristics, a given SAGE sample may fail to capture a large number of expre...
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15 صفحه اولShrinkage Estimation for SAGE Data using a Mixture Dirichlet Prior
Serial Analysis of Gene Expression (SAGE) is a technique for estimating the gene expression profile of a biological sample. Any efficient inference in SAGE must be based upon efficient estimates of these gene expression profiles, which consist of the estimated relative abundances for each mRNA species present in the sample. The data from SAGE experiments are counts for each observed mRNA specie...
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ژورنال
عنوان ژورنال: Biometrics
سال: 2003
ISSN: 0006-341X,1541-0420
DOI: 10.1111/1541-0420.00057